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编 号:F025107
分子式:C22H16N4O
分子量:352.39
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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100mg
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生物活性:
ML347 (LDN193719) is a highly selective ALK1/ALK2 inhibitor. ML347 has IC50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-β1.

体外研究:
ML347 可通过抑制 ALK1/ALK2 来阻断 TGF-β 信号转导。
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