产品
编 号：F210607
分子式：C10H12N2O2S
分子量：224.28
分子式：C10H12N2O2S
分子量：224.28
产品类型
规格
价格
是否有货
1mg
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5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 175340-20-2
产品详情
生物活性：
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests.
体内研究：
S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models .S 18986 (5-50 mg/kg; i.p.) significantly increases both the induction and the maintenance of 4 and 20 bursts tetanus-evoked potentiation.Animal Model:Middle-aged (14-15-months-old) mice
Dosage:0.3, 1, and 10 mg/kg
Administration:p.o.
Result:Showed antiamnesic properties in middle-aged rodents.
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests.
体内研究：
S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models .S 18986 (5-50 mg/kg; i.p.) significantly increases both the induction and the maintenance of 4 and 20 bursts tetanus-evoked potentiation.Animal Model:Middle-aged (14-15-months-old) mice
Dosage:0.3, 1, and 10 mg/kg
Administration:p.o.
Result:Showed antiamnesic properties in middle-aged rodents.
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