产品
编 号:F209415
分子式:C26H40O2
分子量:384.59
产品类型
结构图
CAS No: 174627-50-0
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产品详情
生物活性:
L759633 is a potent and selective agonist of cannabinoid receptor (CB2) receptor, with Kis of 6.4 nM and 1043 nM for CB2 and CB1 receptors, respectively. L759633 can inhibit Forskolin-stimulated cAMP production.
体外研究:
L759633 (0.1-1000 nM) inhibits Forskolin-stimulated cyclic AMP production in CB2-transfected cells, with an EC50 of 8.1 nM.L759633 inhibits Forskolin-stimulated cyclic AMP production by 48% at the concentration of 10 μM.