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编 号:F208151
分子式:C30H53N3O6
分子量:551.76
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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100mg
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生物活性:
Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC50 of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.

体内研究:
Aliskiren (< 10 mg/kg, Orally, daily) inhibits plasma renin activity and lowers blood pressure in sodium-depleted marmosets.Aliskiren (10 mg/kg, Intragastrically, once) significantly alleviates multiple cachexia?associated symptoms in BALB/c mice bearing C26 mouse colon carcinoma cells, including BW loss, tumor burden, muscle wasting, muscular dysfunction, and shortened survival.
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