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编 号：F207473
分子式：C23H22F7N4O6P
分子量：614.41
分子式：C23H22F7N4O6P
分子量：614.41
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CAS No: 172673-20-0
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生物活性：
Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).
体内研究：
Fosaprepitant (30 mg/kg; i.p.; daily; for 7 days) attenuates tolerance to morphine and increases the antinociceptive effect in in rats.Animal Model:Sprague-Dawley rats
Dosage:30 mg/kg
Administration:Intraperitoneal injection, daily, for 7 days
Result:Increased the antinociceptive effect of morphine compared to control group.
Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).
体内研究：
Fosaprepitant (30 mg/kg; i.p.; daily; for 7 days) attenuates tolerance to morphine and increases the antinociceptive effect in in rats.Animal Model:Sprague-Dawley rats
Dosage:30 mg/kg
Administration:Intraperitoneal injection, daily, for 7 days
Result:Increased the antinociceptive effect of morphine compared to control group.
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