产品
编 号:F205876
分子式:C7H13NO4
分子量:175.18
产品类型
结构图
CAS No: 170984-72-2
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产品详情
生物活性:
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an?antidepressant agent.
体外研究:
EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone.