产品
编 号:F203983
分子式:C31H35F6N4O5P
分子量:688.6
产品类型
结构图
CAS No: 1703748-89-3
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产品详情
生物活性:
Fosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor.
体内研究:
Pronetupitant is rapidly and extensively converted to Netupitant after i.v. injection in rats.
体外研究:
Fosnetupitant (Pronetupitant) displays micromolar affinity for the 5-HT6 (pKi ~ 5.2) receptor and type L Ca2+ channels (pKi ~ 5.7) and does not bind all the other proteins investigated.