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编 号:F202239
分子式:C6H10N2O4
分子量:174.15
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生物活性:
(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. (2R,4R)-APDC has anticonvulsant and neuroprotective effects.

体内研究:
2R, 4R-APDC (1-10 nmol; ICV; daily for 14 days) decreases cell proliferation in the dentate gyrus.Animal Model:Adult male Sprague-Dawley rats weighing between 300 and 350 g
Dosage:1 nmol/10 μl; 10 nmol/10μl
Administration:ICV; daily for 14 days
Result:Resulted in decreased BrdU-immunoreactive cells in the DG.
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