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编 号:F202073
分子式:C30H50O
分子量:426.72
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1mg
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5mg
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生物活性:
Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with Kd values of 1.2 μM and 1.4 μM for Trypanosoma brucei (TB) and human CYP51, respectively.

体外研究:
Obtusifoliol (0.1-100 μM; 48 hours) inhibit MCF-7 and MDA-MB231 breast cancer cells proliferation via arresting cell cycle progression and induction of apoptosis.
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