产品
编 号：F201502
分子式：C11H11NO4
分子量：221.21
分子式：C11H11NO4
分子量：221.21
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 168560-79-0
产品详情
生物活性：
UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis.
体内研究：
UPF-523 (0.18 mg/kg; i.p.; 0.5 ml per 100 g) results in a final concentration of 100–150 mM which is below an IC50 of 214 mM.Animal Model:Naive male hooded Lister rats (320–350 g)
Dosage:0.18 mg/kg
Administration:I.p.; 0.5 ml per 100 g
Result:Showed no gross motor abnormalities and normal righting reflexes.
UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis.
体内研究：
UPF-523 (0.18 mg/kg; i.p.; 0.5 ml per 100 g) results in a final concentration of 100–150 mM which is below an IC50 of 214 mM.Animal Model:Naive male hooded Lister rats (320–350 g)
Dosage:0.18 mg/kg
Administration:I.p.; 0.5 ml per 100 g
Result:Showed no gross motor abnormalities and normal righting reflexes.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备