产品
编 号:F199002
分子式:C26H42NNaO5
分子量:471.61
产品类型
结构图
CAS No: 16564-43-5
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产品详情
生物活性:
Glycochenodeoxycholic (GCDC) acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis.
体外研究:
GCDC (50 μM, 2, 4 h) 在暴露后 2 小时使细胞内 PKC 活性降低 44 %,并在暴露后 4 小时诱导 42 % 的离体肝细胞凋亡。