产品
编 号：F198817
分子式：C4H4O5
分子量：132.07
分子式：C4H4O5
分子量：132.07
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
280
In-stock
500mg
询价
询价
结构图
CAS No: 16533-72-5
产品详情
生物活性：
cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system.
体内研究：
cis-Epoxysuccinic acid (1 mg/kg; i.v. once) has an effect on the blood pressure of rats.Animal Model:Male Wistar rats
Dosage:1 mg/kg
Administration:Intravenous injection; 1 mg/kg once
Result:Showed in vivo activity and increased blood pressure after injection.
体外研究：
cis-Epoxysuccinic acid (1-100 μM; 10 min) affects cAMP levels of HEK293 cells.cis-Epoxysuccinic acid (0.1 μM-100 mM; 1 h) agonists SUCNR1 pathways without affects succinate dehydrogenase.
cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system.
体内研究：
cis-Epoxysuccinic acid (1 mg/kg; i.v. once) has an effect on the blood pressure of rats.Animal Model:Male Wistar rats
Dosage:1 mg/kg
Administration:Intravenous injection; 1 mg/kg once
Result:Showed in vivo activity and increased blood pressure after injection.
体外研究：
cis-Epoxysuccinic acid (1-100 μM; 10 min) affects cAMP levels of HEK293 cells.cis-Epoxysuccinic acid (0.1 μM-100 mM; 1 h) agonists SUCNR1 pathways without affects succinate dehydrogenase.
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