产品
编 号：F198421
分子式：C19H14BF4N3O4S
分子量：467.2
分子式：C19H14BF4N3O4S
分子量：467.2
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规格
价格
是否有货
10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 1648843-04-2
产品详情
生物活性：
SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.
体内研究：
SX-682 (50 mg/kg；口服；周一至周五；每天两次) 观察到作为单一药物对 CRPC 进展的影响微弱至中等，但与 ICB 联合产生了强大的效果。Animal Model:C57BL/6NTac-Tyrtm1Arte?female mice
Dosage:50 mg/kg
Administration:Orally; twice a day on a Monday through Friday
Result:Has Meager to moderate effects on CRPC progression.
SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity.
体内研究：
SX-682 (50 mg/kg；口服；周一至周五；每天两次) 观察到作为单一药物对 CRPC 进展的影响微弱至中等，但与 ICB 联合产生了强大的效果。Animal Model:C57BL/6NTac-Tyrtm1Arte?female mice
Dosage:50 mg/kg
Administration:Orally; twice a day on a Monday through Friday
Result:Has Meager to moderate effects on CRPC progression.
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