产品
编 号:F198327
分子式:C7H14N2O3S
分子量:206.26
产品类型
结构图
CAS No: 1646-87-3
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产品详情
生物活性:
Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish.
体外研究:
Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%.Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%.Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%.Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos.