产品
编 号：F197818
分子式：C16H29N3O8
分子量：391.42
分子式：C16H29N3O8
分子量：391.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
询价
询价
500mg
询价
询价
结构图
CAS No: 1642-54-2
产品详情
生物活性：
Diethylcarbamazine citrate is an orally active anthropoidal compound. Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism of filaria microfilaria. Diethylcarbamazine citrate has anti-inflammatory and antiparasitic activity.
体内研究：
Diethylcarbamazine citrate (250 mg/kg, 静脉注射, 单剂量) 在感染白化病的大鼠中可引起 mf 计数早期急剧下降，随后又增加。Diethylcarbamazine citrate (50 mg/kg, 口服, 每周两次) 通过调节脂肪组织炎症改善高脂肪饮食诱导的肥胖小鼠的胰岛素抵抗。Animal Model:HFD-induced obese mice
Dosage:50 mg/kg
Administration:p.o. twice a week
Result:Reduced glucose , triglycerides and insulin levels.Reduced the levels of TNF-α, IL-6 and MCP-1.Reduced COX activity and inhibited this translocated or activated NF-κBp65.
Diethylcarbamazine citrate is an orally active anthropoidal compound. Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism of filaria microfilaria. Diethylcarbamazine citrate has anti-inflammatory and antiparasitic activity.
体内研究：
Diethylcarbamazine citrate (250 mg/kg, 静脉注射, 单剂量) 在感染白化病的大鼠中可引起 mf 计数早期急剧下降，随后又增加。Diethylcarbamazine citrate (50 mg/kg, 口服, 每周两次) 通过调节脂肪组织炎症改善高脂肪饮食诱导的肥胖小鼠的胰岛素抵抗。Animal Model:HFD-induced obese mice
Dosage:50 mg/kg
Administration:p.o. twice a week
Result:Reduced glucose , triglycerides and insulin levels.Reduced the levels of TNF-α, IL-6 and MCP-1.Reduced COX activity and inhibited this translocated or activated NF-κBp65.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备