产品
编 号:F197697
分子式:C26H42NNaO5
分子量:471.61
产品类型
结构图
CAS No: 16409-34-0
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产品详情
生物活性:
Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels.
体内研究:
Glycodeoxycholate Sodium (0.08 mg/kg,鼻腔给药,单次剂量) 联合胰岛素钠使绵羊的葡萄糖水平降低 40%。
体外研究:
Glycodeoxycholate Sodium (1-5 mM, 2h) 对 Caco-2 细胞具有细胞毒性。Glycodeoxycholate Sodium (1-15 mM, 1h) 增加主胰管通透性,导致的胰管细胞间紧密连接破坏和细胞间隙肿胀。