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编 号：F196908
分子式：C22H26ClN
分子量：339.9
分子式：C22H26ClN
分子量：339.9
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CAS No: 16378-22-6
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生物活性：
Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson.
体内研究：
Piroheptine hydrochloride（20 mg/kg；腹腔注射；单剂量，MPTP 注射前 30 分钟）在小鼠模型中抑制 MPTP 的神经毒性。Animal Model:Male 8-week-old C57BL/6J mice (20-30 g)
Dosage:20 mg/kg
Administration:IP; 30 min before MPTP injection (10 mg/kg; 4 times with 1 h interval)
Result:Prevented loss of striatal dopamine.
Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson.
体内研究：
Piroheptine hydrochloride（20 mg/kg；腹腔注射；单剂量，MPTP 注射前 30 分钟）在小鼠模型中抑制 MPTP 的神经毒性。Animal Model:Male 8-week-old C57BL/6J mice (20-30 g)
Dosage:20 mg/kg
Administration:IP; 30 min before MPTP injection (10 mg/kg; 4 times with 1 h interval)
Result:Prevented loss of striatal dopamine.
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