产品
编 号：F196850
分子式：C38H50F2N3O10P
分子量：777.79
分子式：C38H50F2N3O10P
分子量：777.79
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 1637532-77-4
产品详情
生物活性：
PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research.
体内研究：
PM-43I (intranasal administration; 5 μg per mouse; every other day; 18 d) activity is restricted to the lung by intranasal administration.Animal Model:Mice injected with Ovalhumin/Alum
Dosage:5 μg per mouse
Administration:Intranasal administration; 5 μg per mouse; every other day; 18 days
Result:Showed no effect on the sensisization of peripheral spleenocytes to ovalbumin.
体外研究：
PM-43I (0.05-5 μM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Beas-2B immortalized human airway cells.
PM-43I is a potent STAT6 inhibitor and can reduce STAT6 phosphorylation level. PM-43I can be used in allergic lung disease, allergic rhinitis, chronic pulmonary obstructive disease and cancer research.
体内研究：
PM-43I (intranasal administration; 5 μg per mouse; every other day; 18 d) activity is restricted to the lung by intranasal administration.Animal Model:Mice injected with Ovalhumin/Alum
Dosage:5 μg per mouse
Administration:Intranasal administration; 5 μg per mouse; every other day; 18 days
Result:Showed no effect on the sensisization of peripheral spleenocytes to ovalbumin.
体外研究：
PM-43I (0.05-5 μM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Beas-2B immortalized human airway cells.
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