产品
编 号:F196820
分子式:C21H20ClN5O
分子量:393.87
产品类型
结构图
CAS No: 1637300-25-4
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产品详情
生物活性:
AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
体外研究:
AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. AF34394 and related compounds are only of modest potency and are relatively lipophilic (e.g., AF34394 clogP=5.2, LLE=2.1, and 14b clog P=3.1 and LLE=3.2) the series shows promising SAR and represents an excellent start point for further optimization.