产品
编 号：F196465
分子式：MoS42-
分子量：224.22
分子式：MoS42-
分子量：224.22
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CAS No: 16330-92-0
产品详情
生物活性：
Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma.
体内研究：
Tetrathiomolybdate (0.2 mg/小鼠/天; 口服; 10 周)保护小鼠免受胶原诱导的关节炎，具有预防作用。Tetrathiomolybdate (0.03 mg/mL; 加在水中，8 周)通过减少肿胀和红斑抑制小鼠胶原诱导关节炎的进展。Animal Model:Collagen-induced arthritis model in mice
Dosage:0.2 mg/mouse/day or 0.03 mg/mL, added in water
Administration:Oral gavage, for 10 weeks; Collagen injected at weeks 2
Result:Showed significant preventive effect and protective effect in mice.
Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma.
体内研究：
Tetrathiomolybdate (0.2 mg/小鼠/天; 口服; 10 周)保护小鼠免受胶原诱导的关节炎，具有预防作用。Tetrathiomolybdate (0.03 mg/mL; 加在水中，8 周)通过减少肿胀和红斑抑制小鼠胶原诱导关节炎的进展。Animal Model:Collagen-induced arthritis model in mice
Dosage:0.2 mg/mouse/day or 0.03 mg/mL, added in water
Administration:Oral gavage, for 10 weeks; Collagen injected at weeks 2
Result:Showed significant preventive effect and protective effect in mice.
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