产品
编 号:F196393
分子式:C19H18ClF2N3O3.3/2H2O
分子量:436.84
产品类型
结构图
CAS No: 163253-35-8
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产品详情
生物活性:
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections.
体内研究:
Sitafloxacin hydrate (2-10 mg/kg) 在小鼠体内表现出良好的抗鸟分枝杆菌活性,可有效消除脾脏、肺内的细菌,对巨噬细胞内分枝杆菌表现出强的活性。
体外研究:
Sitafloxacin hydrate 对鸟分支杆菌的最低抑菌浓度(MIC)、最低杀菌浓度(MBC)和突变预防浓度(MPC)分别为 2 mg/L,2 mg/L 和 45 mg/L。