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编 号:F023349
分子式:C18H22F2N4O
分子量:348.39
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
BMY 14802 is a sigma-1 receptor (σ1R) antagonist, as well as an agonist at serotonin (5-HT) 1A and adrenergic alpha-1 receptors. BMY 14802 inhibits abnormal involuntary movement (AIM) in rat Parkinson's disease (PD) model, with down-regulating the expression of AIM.

体内研究:
BMY 14802 (15 mg/kg;腹腔注射;单次剂量) 在大鼠 PD 模型中显著抑制 AIM 并减少运动障碍,尤其是在处理后的第一个小时。
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