产品
编 号:F002544
分子式:C17H20N2O2
分子量:284.35
产品类型
结构图
CAS No: 1004548-96-2
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产品详情
生物活性:
FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2-containing membranes with an IC50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices.
体外研究:
FFN511 (350 nM; 30 min) accumulats in a pattern consistent with LDCVs in cultured mouse chromaffin cells, and the accumulation is abolished by the lipophilic base chloroquine.