产品
编 号:F195278
分子式:C22H27N5O
分子量:377.48
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.

体外研究:
HQL-79 是一种针对底物 PGH2 的竞争性抑制剂,同时也是一种针对 GSH 的非竞争性抑制剂。
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