产品
编 号：F194752
分子式：C20H17F2N5O2
分子量：397.38
分子式：C20H17F2N5O2
分子量：397.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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结构图
CAS No: 1622849-43-7
产品详情
生物活性：
GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM .
体外研究：
GSK3145095 potently blocks the TNF response as shown by determination of overall cell viability as measured by cellular ATP levels (IC50 = 1.6 nM), cell death as measured by LDH release (IC50 = 0.5 nM) and RIP1-dependent inflammatory cytokine MIP-1β production, either as absolute levels for protein, or fold changes in mRNA expression (IC50 = 0.4 nM) .
GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM .
体外研究：
GSK3145095 potently blocks the TNF response as shown by determination of overall cell viability as measured by cellular ATP levels (IC50 = 1.6 nM), cell death as measured by LDH release (IC50 = 0.5 nM) and RIP1-dependent inflammatory cytokine MIP-1β production, either as absolute levels for protein, or fold changes in mRNA expression (IC50 = 0.4 nM) .
产品资料
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