产品
编 号：F194009
分子式：C19H19N3O3
分子量：337.37
分子式：C19H19N3O3
分子量：337.37
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 161832-65-1
产品详情
生物活性：
Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain.
体内研究：
Talampanel (orally administration; 5 mg/kg; once a day; 2 weeks) reduces motoneuronal calcium in a mouse model of ALS, but its efficacy declines as the disease progresses.Animal Model:Female mutant SOD1 Tg mice
Dosage:5 mg/kg
Administration:Orally administration; 5 mg/kg; once a day; 2 weeks
Result:Had a significant effect in reducing the calcium level only at the age of 12 weeks.
Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain.
体内研究：
Talampanel (orally administration; 5 mg/kg; once a day; 2 weeks) reduces motoneuronal calcium in a mouse model of ALS, but its efficacy declines as the disease progresses.Animal Model:Female mutant SOD1 Tg mice
Dosage:5 mg/kg
Administration:Orally administration; 5 mg/kg; once a day; 2 weeks
Result:Had a significant effect in reducing the calcium level only at the age of 12 weeks.
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