产品
编 号：F193985
分子式：C13H15Cl2N7O
分子量：356.21
分子式：C13H15Cl2N7O
分子量：356.21
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 161804-20-2
产品详情
生物活性：
Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.
体内研究：
Benzamil hydrochloride (Benzylamiloride hydrochloride) (0.7 mg/kg/天；sc) 处理的中风倾向自发性高血压大鼠 (SHRSP) 在 SHRSP 大鼠中平均存活至 16.1 周龄。
体外研究：
Benzamil hydrochloride (Benzylamiloride hydrochloride) 抑制神经元和异源表达的小电导 Ca2+-激活的 K2+ 通道。
Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.
体内研究：
Benzamil hydrochloride (Benzylamiloride hydrochloride) (0.7 mg/kg/天；sc) 处理的中风倾向自发性高血压大鼠 (SHRSP) 在 SHRSP 大鼠中平均存活至 16.1 周龄。
体外研究：
Benzamil hydrochloride (Benzylamiloride hydrochloride) 抑制神经元和异源表达的小电导 Ca2+-激活的 K2+ 通道。
产品资料
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