产品
编 号:F193770
分子式:C22H28N4O2
分子量:380.48
产品类型
结构图
CAS No: 1616391-87-7
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产品详情
生物活性:
GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM.
体外研究:
GSK591 (5 μM; MCF7, T47D, and MCF10A cells) treatment suppresses breast cancer stem cells (BCSCs) proliferation and self-renewal. GSK591 reduces BCSCs numbers in vitro.