产品
编 号:F191498
分子式:C35H41Cl2N3O2
分子量:606.62
产品类型
结构图
CAS No: 160492-56-8
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生物活性:
Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia.
体内研究:
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time. Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time. Animal Model:Male Mongolian gerbils of 7 weeks old (50-60 g)
Dosage:1, 3 and 10 mg/kg
Administration:Po; 60 min before testing
Result:Significantly increased social interaction time.