产品
编 号:F190578
分子式:C8H18ClN
分子量:163.69
产品类型
结构图
CAS No: 15991-59-0
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产品详情
生物活性:
(±)-Coniine hydrochloride (2-Propylpiperidine hydrochloride) is a potent nAChR agonist with an EC50 value of 0.3 mM. (±)-Coniine hydrochloride shows acute toxicity with an LD50 value of 7.7 mg/kg.
体内研究:
(±)-Coniine hydrochloride (compound 1) (0.05 mg-0.2 mg; i.v.) 具有急性毒性,LD50 值为 7.7 mg/kg。Animal Model:15-20 g, Swiss-Webster male mice
Dosage:0.05 mg-0.2 mg
Administration:I.v.
Result:Clinical signs was almost immediate after injection, beginning with piloerection, tailflicking, and rapidly progressing to intention tremors, clonic convulsions, muscular weakness, lateral recumbency, and death; shows acute toxicity with an LD50 value of 7.7 mg/kg.