产品
编 号:F190304
分子式:C20H20BrClN2O
分子量:419.74
产品类型
结构图
CAS No: 1597489-14-9
联系客服
产品详情
生物活性:
ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity.
体内研究:
ML401 shows very good stability in both human plasma and mouse plasma.
体外研究:
ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM).