产品
编 号：F190189
分子式：C6H12N2O3
分子量：160.17
分子式：C6H12N2O3
分子量：160.17
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
5g
608
In-stock
结构图
CAS No: 1596-84-5
产品详情
生物活性：
Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested.
体内研究：
Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
体外研究：
Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).
Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested.
体内研究：
Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
体外研究：
Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).
产品资料
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