产品
编 号：F188977
分子式：C25H23ClF4N4O3
分子量：538.92
分子式：C25H23ClF4N4O3
分子量：538.92
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1587727-31-8
产品详情
生物活性：
PF-06648671?is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease.
体内研究：
PF-06648671 demonstrates reduces Aβ42 within the brain and CSF following acute oral administration in animals.
体外研究：
In a cell-based assay, PF-06648671 reduces Aβ42 and Aβ40 , with concomitant increases in Aβ37 and Aβ38, without inhibiting the cleavage of Notch or other substrates.
PF-06648671?is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease.
体内研究：
PF-06648671 demonstrates reduces Aβ42 within the brain and CSF following acute oral administration in animals.
体外研究：
In a cell-based assay, PF-06648671 reduces Aβ42 and Aβ40 , with concomitant increases in Aβ37 and Aβ38, without inhibiting the cleavage of Notch or other substrates.
产品资料
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