产品
编 号：F188595
分子式：C32H50N4O8
分子量：618.76
分子式：C32H50N4O8
分子量：618.76
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 158442-41-2
产品详情
生物活性：
PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas.
体外研究：
PSI (24 h) inhibits the proliferation of primary effusion lymphoma (PEL) cells at low nanomolar concentrations (CC50s of 205, 190, 22.0, 53.0 nM FOR BJAB, Ramos, BC3, BCBL1 cells, respectively).PSI (50 nM; 6 h) increases caspase-3/7 activity by 8-fold compared with control.PSI (50 nM; 6 h) decreases the transcriptional activity of NF-κB by 52%.PSI (1, 5 nM; 3 days) inhibits the growth of BC3 cells at a high concentration (5 nM).
PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas.
体外研究：
PSI (24 h) inhibits the proliferation of primary effusion lymphoma (PEL) cells at low nanomolar concentrations (CC50s of 205, 190, 22.0, 53.0 nM FOR BJAB, Ramos, BC3, BCBL1 cells, respectively).PSI (50 nM; 6 h) increases caspase-3/7 activity by 8-fold compared with control.PSI (50 nM; 6 h) decreases the transcriptional activity of NF-κB by 52%.PSI (1, 5 nM; 3 days) inhibits the growth of BC3 cells at a high concentration (5 nM).
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