产品
编 号：F187893
分子式：C11H13NO6
分子量：255.22
分子式：C11H13NO6
分子量：255.22
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 1577222-14-0
产品详情
生物活性：
Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity.
体内研究：
Diroximel fumarate (60-100 mg/kg，口服，每日一次，5 天) 可预防雄性和雌性野生型 C57BL/6 小鼠中 MGO 诱导的机械过敏和冷过敏反应。
Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity.
体内研究：
Diroximel fumarate (60-100 mg/kg，口服，每日一次，5 天) 可预防雄性和雌性野生型 C57BL/6 小鼠中 MGO 诱导的机械过敏和冷过敏反应。
产品资料
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