产品
编 号:F187811
分子式:C14H15NO2S
分子量:261.34
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1g
168
In-stock
5g
504
In-stock
结构图
联系客服
产品详情
生物活性:
BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC50s of ~5 μM for actin- and Ca2+-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers.

体外研究:
BTS (2-12 μM) inhibits the Ca2+-stimulated ATPase activity of myosin S1 in the absence of actin, with an IC50 of ~5 μM.BTS (2-20 μM) reversibly inhibits the gliding motility rate of heavy meromyosin (HMM).BTS (100 μM) releases myosin from actin in the presence of ADP.BTS (0-20 μM) reversibly inhibits isometric Ca2+-activated tension in skinned skeletal muscle fibres from rabbit and frog, with IC50s of ~3 μM and 1 μM, respectively.
产品资料