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编 号:F187496
分子式:C25H35ClO6
分子量:466.99
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生物活性:
Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM.

体内研究:
Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis.Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey.Animal Model:Male mice (50–80 days)
Dosage:25 μg/kg
Administration:Intraperitoneal injection; daily, for 4 weeks
Result:Stimulated the androgen synthesis in a time-dependent manner.
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