产品
编 号：F187238
分子式：C34H56
分子量：485.53
分子式：C34H56
分子量：485.53
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 157009-81-9
产品详情
生物活性：
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa).
体内研究：
GPRP acetate (100 mg/kg；腹腔注射，每天一次，持续 10 天) 通过改善体重减轻和死亡率显著缓解葡聚糖硫酸钠 (DSS) 诱导的结肠炎。Animal Model:C57BL/6 mice with dextran sulphate sodium (DSS)-induced colitis
Dosage:100 mg/kg
Administration:Intraperitoneal injection; 100 mg/kg, once daily, for 10 days
Result:Significantly inhibited body weight loss and reduced DSS-induced mortality and shortening of colon length, and decreased tissue damage and infiltration of inflammatory cells in colitis mice. Decreased levels of inflammatory cytokines in colitis mice.
体外研究：
GPRP acetate (0，2 和 4 mM) 增加游离凝血酶生成。
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa).
体内研究：
GPRP acetate (100 mg/kg；腹腔注射，每天一次，持续 10 天) 通过改善体重减轻和死亡率显著缓解葡聚糖硫酸钠 (DSS) 诱导的结肠炎。Animal Model:C57BL/6 mice with dextran sulphate sodium (DSS)-induced colitis
Dosage:100 mg/kg
Administration:Intraperitoneal injection; 100 mg/kg, once daily, for 10 days
Result:Significantly inhibited body weight loss and reduced DSS-induced mortality and shortening of colon length, and decreased tissue damage and infiltration of inflammatory cells in colitis mice. Decreased levels of inflammatory cytokines in colitis mice.
体外研究：
GPRP acetate (0，2 和 4 mM) 增加游离凝血酶生成。
产品资料
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