产品
编 号：F187119
分子式：C19H23NO3
分子量：313.39
分子式：C19H23NO3
分子量：313.39
产品类型
规格
价格
是否有货
结构图
CAS No: 15687-41-9
产品详情
生物活性：
Oxyfedrine, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine can be used in the research of cardiovascular disease.
体内研究：
Oxyfedrine (14 mg/kg, p.o., for 3-4 weeks) shows anti-anginal action in cats. Oxyfedrine (10 mg/kg, i.p., HCT116 cell xenograft mice) suppresses tumor growth when combined with sulfasalazine (SSZ, 350 mg/kg, i.p.).Oxyfedrine (1 mg/kg, i.v.) decreases the arterial and venous blood high blood viscosity (HBV) in ice water stress rats.Animal Model:Cats
Dosage:14 mg/kg
Administration:Oral administration (p.o.), for 3-4 weeks.
Result:Decreased systolic and diastolic blood pressures, increased heart rate and cardiac output.
体外研究：
Oxyfedrine (50 μM, 48 h) suppresses aldehyde dehydrogenase (ALDH) activity in HCT116 and HSC-4 cells.Oxyfedrine (50 μM, 48 h) acts as a sensitizer for GSH-depleting agents, and induces cell death in HCT116 and HSC-4 cells when with the drug combinations.Oxyfedrine (0-1 μg/mL) inhibits spontaneous myogenic activity in rat isolated portal vein.
Oxyfedrine, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine can be used in the research of cardiovascular disease.
体内研究：
Oxyfedrine (14 mg/kg, p.o., for 3-4 weeks) shows anti-anginal action in cats. Oxyfedrine (10 mg/kg, i.p., HCT116 cell xenograft mice) suppresses tumor growth when combined with sulfasalazine (SSZ, 350 mg/kg, i.p.).Oxyfedrine (1 mg/kg, i.v.) decreases the arterial and venous blood high blood viscosity (HBV) in ice water stress rats.Animal Model:Cats
Dosage:14 mg/kg
Administration:Oral administration (p.o.), for 3-4 weeks.
Result:Decreased systolic and diastolic blood pressures, increased heart rate and cardiac output.
体外研究：
Oxyfedrine (50 μM, 48 h) suppresses aldehyde dehydrogenase (ALDH) activity in HCT116 and HSC-4 cells.Oxyfedrine (50 μM, 48 h) acts as a sensitizer for GSH-depleting agents, and induces cell death in HCT116 and HSC-4 cells when with the drug combinations.Oxyfedrine (0-1 μg/mL) inhibits spontaneous myogenic activity in rat isolated portal vein.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备