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编 号：F187104
分子式：C11H14N2S
分子量：206.31
分子式：C11H14N2S
分子量：206.31
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CAS No: 15686-83-6
产品详情
生物活性：
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
体内研究：
Pyrantel (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.Animal Model:Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected).
Dosage:10 mg/kg
Administration:Oral administration; single.
Result:Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
体外研究：
Pyrantel (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity.
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
体内研究：
Pyrantel (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.Animal Model:Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected).
Dosage:10 mg/kg
Administration:Oral administration; single.
Result:Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
体外研究：
Pyrantel (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity.
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