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编 号:F184640
分子式:C27H28N6O3
分子量:484.55
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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生物活性:
CCK-B Receptor Antagonist 2, compound 15b, is a potent and orally active Gastrin/CCK-B antagonist with an IC50 value of 0.43 nM. CCK-B Receptor Antagonist 2 also inhibits gastrin/CCK-A activity with an IC50 of 1.82 μM.

体内研究:
CCK-B Receptor Antagonist 2 (0.1 μmol/kg; intravenous injection) has an inhibition effect on pentagastrin-induced gastric acid secretion in anethsetized rats with an ED50 of 8.3 nmol/kg.
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