产品
编 号:F182763
分子式:C18H20F3N5S
分子量:395.45
产品类型
结构图
CAS No: 1542213-00-2
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产品详情
生物活性:
NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH.
体外研究:
NCT-502 对 MDA-MB-468 具有细胞毒性,EC50 为 15.2 μM。