产品
编 号:F181968
分子式:C13H11N
分子量:181.24
产品类型
结构图
CAS No: 153-78-6
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产品详情
生物活性:
2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis.
体内研究:
2-Aminofluorene (60 mg/kg, i.p.) accumulates twice the 2-Aminofluorene-DNA adducts of slow acetylators (A/J) in rapid acetylator mice (C57BL/6J).2-Aminofluorene (60 mg/kg, i.p.) forms significantly higher levels of DNA adducts in tumor-target organs than in non-target organs in acetylator congenic hamsters.
体外研究:
2-Aminofluorene (0-100 μM, 1-5 days) produces a dose-related suppression of the antibody response to sheep erythrocytes (SRBC), DNP-Ficoll, and LPS.2-Aminofluorene (0-100 μM, 3 days, spleen cells) produces suppression on lymphoproliferative responses to LPS and Con A.