产品
编 号：F181492
分子式：C24H32N4O11
分子量：552.53
分子式：C24H32N4O11
分子量：552.53
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CAS No: 153473-94-0
产品详情
生物活性：
Carbazeran (citrate), a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran (citrate) can be used for the research of metabolic disease.
体内研究：
Carbazeran (10 mg/kg; p.o.) (citrate) of the unmetabolized in samples from humanized-liver mice, the mean plasma concentrations are lower than in those from control mice for 0.5~4 hours after oral administration.Oral administration of carbazeran (citrate) to guinea pigs has reportedly resulted in large kinetic deuterium isotope effects on the AUC and Cmax, without a change of systemic half-life.Animal Model:Mice
Dosage:10 mg/kg
Administration:P.o.
Result:The mean plasma concentrations were lower than in those from control mice for 0.5~4 hours after oral administration.
Carbazeran (citrate), a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran (citrate) can be used for the research of metabolic disease.
体内研究：
Carbazeran (10 mg/kg; p.o.) (citrate) of the unmetabolized in samples from humanized-liver mice, the mean plasma concentrations are lower than in those from control mice for 0.5~4 hours after oral administration.Oral administration of carbazeran (citrate) to guinea pigs has reportedly resulted in large kinetic deuterium isotope effects on the AUC and Cmax, without a change of systemic half-life.Animal Model:Mice
Dosage:10 mg/kg
Administration:P.o.
Result:The mean plasma concentrations were lower than in those from control mice for 0.5~4 hours after oral administration.
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