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编 号：F177942
分子式：C21H24Cl2FNO2
分子量：412.33
分子式：C21H24Cl2FNO2
分子量：412.33
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CAS No: 1511-16-6
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生物活性：
Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
体内研究：
Haloperidol (1 mg) intra-arterially attenuates the dopamine-induced pancreatic secretion. Haloperidol (3 mg) completely inhibits the action of 10 μg of dopamine in the pancreas of the dogs. Haloperidol (10 mg/kg) as well as chlorpromazine (CPZ, 15 mg/kg) blocks mescaline-induced altered behavior within 7 to 10 minutes when injected into the mice 45 minutes after 50 mg/kg (2 μc) of mescaline. Haloperidol has no effect on mescaline disappearance.
Haloperidol hydrochloride is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
体内研究：
Haloperidol (1 mg) intra-arterially attenuates the dopamine-induced pancreatic secretion. Haloperidol (3 mg) completely inhibits the action of 10 μg of dopamine in the pancreas of the dogs. Haloperidol (10 mg/kg) as well as chlorpromazine (CPZ, 15 mg/kg) blocks mescaline-induced altered behavior within 7 to 10 minutes when injected into the mice 45 minutes after 50 mg/kg (2 μc) of mescaline. Haloperidol has no effect on mescaline disappearance.
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