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编 号：F177864
分子式：C20H28FN3O6
分子量：425.45
分子式：C20H28FN3O6
分子量：425.45
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CAS No: 151060-21-8
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生物活性：
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections.
体内研究：
Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters.Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits.
体外研究：
Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs).Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL.Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL.
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections.
体内研究：
Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters.Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits.
体外研究：
Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs).Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL.Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL.
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