产品
编 号：F177653
分子式：C23H30N4O2S
分子量：426.57
分子式：C23H30N4O2S
分子量：426.57
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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100mg
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结构图
CAS No: 150915-41-6
产品详情
生物活性：
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research.
体内研究：
Perospirone (SM-9018 free base；1.0-10.0 mg/kg/天；口服；连续 14 天) 以剂量依赖性方式显著减轻 PCP 诱导的小鼠认知缺陷。Animal Model:Male ICR mice (6 weeks old) weighing 25-30 g
Dosage:1.0, 3.0 or 10.0 mg/kg
Administration:Orally; daily; for 14 consecutive days
Result:Significantly attenuated PCP-induced cognitive deficits in mice in a dose-dependent manner.
体外研究：
Perospirone (SM-9018 free base) 对 α1、5-HT1 和 D1 受体具有中等亲和力 (Ki=17、18 和 41 nM)。
Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone is an atypical antipsychotic agent and has the potential for schizophrenic disease research.
体内研究：
Perospirone (SM-9018 free base；1.0-10.0 mg/kg/天；口服；连续 14 天) 以剂量依赖性方式显著减轻 PCP 诱导的小鼠认知缺陷。Animal Model:Male ICR mice (6 weeks old) weighing 25-30 g
Dosage:1.0, 3.0 or 10.0 mg/kg
Administration:Orally; daily; for 14 consecutive days
Result:Significantly attenuated PCP-induced cognitive deficits in mice in a dose-dependent manner.
体外研究：
Perospirone (SM-9018 free base) 对 α1、5-HT1 和 D1 受体具有中等亲和力 (Ki=17、18 和 41 nM)。
产品资料
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