产品
编 号：F176773
分子式：C28H27Cl2N3O7S
分子量：620.5
分子式：C28H27Cl2N3O7S
分子量：620.5
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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结构图
CAS No: 150375-75-0
产品详情
生物活性：
SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a Ki vaule of 1.4 nM.
体内研究：
SR 49059 (SR-49059) (2 mg/kg and 30 mg/kg; i.p.; once) shows neuroprotective effects in ischemic brain injury when injected early after occlusion of the middle cerebral artery (MCA).Animal Model:Male Wistar rats, weighing 300 to 350 g, cerebral focal ischemia model
Dosage:2 mg/kg and 30 mg/kg dissolved in 10% dimethyl sulfoxide
Administration:Intraperitoneal injection, once
Result:Significantly reduced infarction volume measured at 48 hours after the arterial occlusion. Reduced neurological deficits and ischemic brain edema.
SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a Ki vaule of 1.4 nM.
体内研究：
SR 49059 (SR-49059) (2 mg/kg and 30 mg/kg; i.p.; once) shows neuroprotective effects in ischemic brain injury when injected early after occlusion of the middle cerebral artery (MCA).Animal Model:Male Wistar rats, weighing 300 to 350 g, cerebral focal ischemia model
Dosage:2 mg/kg and 30 mg/kg dissolved in 10% dimethyl sulfoxide
Administration:Intraperitoneal injection, once
Result:Significantly reduced infarction volume measured at 48 hours after the arterial occlusion. Reduced neurological deficits and ischemic brain edema.
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