产品
编 号：F176017
分子式：C17H22N2O3
分子量：302.37
分子式：C17H22N2O3
分子量：302.37
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 149950-60-7
产品详情
生物活性：
Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity.
体内研究：
Tthe approximate lethal oral dose of Emivirine (EMV) for rats was ≥3 g/kg for males and 2.5 g/kg for females.Animal Model:Male Sprague-Dawley rats.
Dosage:50 mg/kg.
Administration:Gavage.
Result:The oral absorption was 68%.
体外研究：
Emivirine (EMV) is also specific for HIV-1 RT and was without effect on HIV-2.Emivirine (EMV) has no obvious toxicity for human healthy cells.
Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity.
体内研究：
Tthe approximate lethal oral dose of Emivirine (EMV) for rats was ≥3 g/kg for males and 2.5 g/kg for females.Animal Model:Male Sprague-Dawley rats.
Dosage:50 mg/kg.
Administration:Gavage.
Result:The oral absorption was 68%.
体外研究：
Emivirine (EMV) is also specific for HIV-1 RT and was without effect on HIV-2.Emivirine (EMV) has no obvious toxicity for human healthy cells.
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