产品
编 号:F175857
分子式:C5H7NO3
分子量:129.11
产品类型
结构图
CAS No: 149-87-1
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产品详情
生物活性:
DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action.
体内研究:
DL-Pyroglutamic acid (0.775 mM/L) completely abolishes the myoclonic jerks and EEG spikes in rats model of epileptic by cobalt implantation in the sensorimotor cerebral cortex.
体外研究:
DL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively.DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford.